quality of life after total thyroidectomy

The search strategy is partially based on CADTH databases search filters for health utilities and quality of life [21]. Of note, in one study, this impairment in social functioning was no longer statistically significant after two years following TT, although it was still significant at this time point for patients who underwent HT [67]. Patient-reported outcomes following total thyroidectomy and lobectomy in thyroid cancer survivors: An analysis of the PROFILES Registry data. More studies have focused on postoperative HrQoL in TT patients, and highlight the fact that HrQoL may be decreased in this patient population compared with the general population. Second, the vast majority of included articles were cross-sectional, which limits the establishment of causal relationships. For the purposes of this review, any surgical intervention restricted to one lobe of the thyroid, with or without isthmusectomy, was classified as a HT (lobectomy). One study compared patients preoperative and postoperative social-related HrQoL following TT, while no study evaluated this aspect in HT patients [68]. Quality-of-life outcomes in Graves disease patients after total Wu H.-X., Zhong H., Xu Y.-D., Xu C.-P., Zhang Y., Zhang W. Psychological and behavioral intervention improves the quality of life and mental health of patients suffering from differentiated thyroid cancer treated with postoperative radioactive iodine-131. [(accessed on 26 February 2022)]. 2015 american thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: The american thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer. The study comparing TT and HT patients found that TT patients more often reported issues with overall physical health, medication, voice, fatigue, throat or neck discomfort, and other physical symptoms, while HT patients more commonly reported weight concerns and autonomic symptoms [71]. The types of analyses used ranged from grounded theory analysis (n = 2) to content analysis (n = 2) and thematic analysis (n = 1) [69,70,71,72,73]. Symptom scores were collected before surgery, short term within 30 days of surgery, and long term 30 days or more after surgery. Each subscale is scored from 4 to 20 and converted to a global fatigue score ranging from 20 to 100, with higher scores indicating more impairment [46]. Patient-reported symptoms, including quality of life and thyroid-specific symptoms, of Graves patients improved significantly from their baseline prior to surgery both shortly after and longer after the surgery, the researchers wrote. One potential problem that can happen after thyroid surgery is damage to the parathyroid glands that results in a low parathyroid hormone level. Bel-Drabe N., Steinert H., Moergeli H., Weidt S., Seiler A., Jenewein J. Thyroid cancer has a small impact on patientpartner relationships and their frequency of sexual activity. The study cohort had a significant improvement in total symptom burden short term after surgery (RR = 0.67; 95% CI, 0.53-0.85) but not long term. Crevenna R., Zettinig G., Keilani M., Posch M., Schmidinger M., Pirich C., Nuhr M., Wolzt M., Quittan M., Fialka-Moser V., et al. Bongers P.J., Greenberg C.A., Hsiao R., Vermeer M., Vriens M.R., Lutke Holzik M.F., Goldstein D.P., Devon K., Rotstein L.E., Sawka A.M., et al. Linking clinical variables with health-related quality of life. Qualitative Studies in Quality of Life: Methodology and Practice. Publishers Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. One study including long-term DTC survivors having undergone TT (on average 5.5 years prior) found that TT patients had improved global HrQoL compared with the general population [53]. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework was used to guide the search and the reporting of the review [20]. The fact that psychological-related HrQoL did not decrease but increased in some studies following surgery compared with preoperative time points further supports this hypothesis. Five of these studies found significant impairment in social-related HrQoL in TT patients compared with the general population for at least one of the following items: social functioning and interactions (n = 4), role limitations due to emotional or physical health (n = 5), and reduced activity (n = 1) [18,51,53,55,58,61]. These symptoms were often reported in association with regrets or dissatisfaction with treatment or the healthcare system in general [69,72]. The https:// ensures that you are connecting to the Radiofrequency Ablation Safe, Effective in Metastatic Papillary Microcarcinomas of the Thyroid. Sintonen H. The 15D instrument of health-related quality of life: Properties and applications. Gotay C.C., Pagano I.S. Development of a disease-specific health-related quality of life questionnaire (THYCA-QoL) for thyroid cancer survivors. Table of Contents | PDF File for Saving and Printing, Quality of life after thyroid cancer surgery is decreased if parathyroid hormone levels are low after surgery, Change In Thyroid Nodule Volume Calculator, Find an Endocrinology Thyroid Specialist, Clinical Thyroidology for the Public (CTFP). It is well-known that more extensive surgeries (i.e., TT) are associated with an increased risk for intra- and postoperative complications (e.g., temporary or permanent recurrent laryngeal nerve palsy and hypoparathyroidism), which are expected to negatively impact patients HrqOL [14] For this reason, it has been hypothesized that HT, in addition to being a viable option from an oncologic standpoint, could be associated with a better postoperative HrQoL in low-risk DTC patients. In fact, everyone must have at least one functioning parathyroid gland to have normal body calcium levels. Stern A.F. An empirical evaluation of the SF-12, SF-6D, EQ-5D and Michigan hand outcome questionnaire in patients with rheumatoid arthritis of the hand. Scores are derived into an EQ-5D index value. The THYCA-QoL is a 24-item questionnaire that was designed specifically to assess HrQoL in thyroid cancer survivors. Health-related quality of life analysis in differentiated thyroid Watt T., Hegeds L., Groenvold M., Bjorner J.B., Rasmussen .K., Bonnema S.J., Feldt-Rasmussen U. Validity and reliability of the novel thyroid-specific quality of life questionnaire, ThyPRO. Health-related quality of life (HrQoL) is a major concern for patients with differentiated thyroid carcinoma (DTC). The .gov means its official. All items are scored on a scale of 1 to 7, which is then transformed into a global score of 0 to 100 [39]. In this review, 16 studies reporting on social functioning through 10 different instruments (SF-12, SF-36, MFI-20, ThyPRO, FoP-Q-SF, FoP, EORTC QLQ-C30, EORTC QLQ-THY34, KT-QoL, 15D) were identified [18,34,51,52,53,54,55,56,57,58,59,61,62,65,67,68]. d FTC: follicular thyroid carcinoma. However, the impact of thyroid surgery extent on patients health-related quality of life (HrQoL) remains poorly characterized in the literature. Global PSQI scores range from 0 to 21, where lower scores denote better sleep quality [47]. . Jacobson B.H., Johnson A., Grywalski C., Silbergleit A., Jacobson G., Benninger M.S., Newman C.W. 15D index scores range from 0 to 1, higher scores denoting better HrQoL [34,35]. A system review and meta-analysis found that the use of radiofrequency ablation for low-risk metastatic papillary microcarcinomas of the thyroid was safe and effective. Strategies to address incomplete follow-up were utilized? Relationships with the healthcare system could either be perceived as a source of anxiety or a source of support and strength by TT patients. and R.J.P. Studies including patients with medullary or anaplastic thyroid cancer were excluded. in the United States [42]. Quality assessment of cross-sectional studies. Nonetheless, it appears clear that DTC patients frequently struggle with both physical and psychological symptoms following surgery. A score from 1 to 4 is attributed to each item, then transformed into a scale ranging from 0 to 100, with higher values indicating more impairment [40]. The study authors concluded that low parathyroid hormone levels following thyroid cancer surgery significantly decrease quality of life. Potential contributing factors include lingering physical symptoms (e.g., associated with calcium homeostasis issues, thyroid hormones imbalances, or voice impairment), the uncertainty regarding general health status, and concerns about the potential financial, psychological, and relational impacts of the DTC cancer diagnosis and its treatment [9] Given the high long-term survival rates and rising incidence of DTC, HrQoL remains a major concern for thyroid cancer patients and is an important factor to address during discussions surrounding therapeutic plans and long-term management. Follow-up was complete, and if not, reasons for loss to follow-up were explored? Mahendran R., Liu J., Kuparasundram S., Griva K. Validation of the english and simplified mandarin versions of the fear of progression questionnaireshort form in chinese cancer survivors. One study observed significantly more anxiety, depression, emotional functioning impairment, and psychological symptoms at one month postoperatively in TT patients versus HT patients [65]. Surgery for papillary thyroid carcinoma: Is lobectomy enough? Addressing postoperative HrQoL when discussing therapeutic options with patients is an integral part of patient-centered care and informed shared decision making, and should be approached in a holistic manner, accounting for its physical, psychological, social, and global aspects. HrQoL is a multidimensional concept including physical and psychological symptoms, social wellbeing, and symptoms associated with illness or treatment [23]. Qualitative studies are valuable in HrQoL research, as they allow for the consideration of individuals perceptions and interpretations; the understanding of their experiences of wellbeing; and the discovery of new issues related to HrQoL [74]. Q8. Parathyroid hormone (PTH): the hormone that regulates the bodys calcium levels. So far, the psychological aspect of HrQoL in DTC patients has been poorly studied, with the majority of existing research focusing on the physical aspects of the disease and related treatments [81]. Adequate physical and psychological statuses indeed allow for healthy social functioning, which thus perhaps represents a more outcome-based component of HrQoL. Anxiety and fear of recurrence despite a good prognosis: An interview study with differentiated thyroid cancer patients.
Uniqlo Ines De La Fressange Fall/winter 2021, Articles Q